ITGA2B and pancreatic ductal adenocarcinoma: In addition, Odaka et al. [165] found that the number of serum PEVs (CD41+-EVs and CD61+-EVs) was significantly higher in patients with pancreatic ductal adenocarcinoma (PDAC) than in healthy controls and that the areas (AUCs) under the receiver operating characteristic (ROC) curves of CD41+-EVs and CD61+-EVs were 0.678 and 0.652, respectively, indicating that they performed moderately well as diagnostic markers and could assist in diagnosing PDAC.