Quantitative analysis after gargling with Nimotuzumab-ICG (0.4 mg/ml) showed that EGFR expression was specifically highly expressed in tumor tissues but not in normal mucosa tissues (Fig. 6A, top, 23.9 ± 1.17 vs 3.01 ± 0.24, **** P < 0.0001). Here, EGFR is linked to neoplasm.