Notably, these focus areas correlated intuitively with HER2 (3+) expression regions, characterized by a high tumor-to-stroma ratio (over 50%), well-differentiated tumor glands, abundant tumor-associated immune cell infiltration, and significant desmoplastic stroma surrounding tumor cells, suggesting that MuMo effectively deduces vital tumor information for predictions (Fig. 5a and Supplementary Fig. S8). The gene discussed is ERBB2; the disease is neoplasm.