Additionally, the outcomes revealed a significant upsurge in the hepatic expression of miR-1205, miR-6881-5p, miR-650, miR-6807-5p, and SPARCL1-1:2 in the two NASH groups (NASH-12wk and NASH-9wk) compared to the Normal group. This evidence concerns the gene SPARCL1 and metabolic dysfunction-associated steatohepatitis.