A hallmark feature in the laboratory assessment of JTA, in contrast to GCA, is the normality of serum acute phase reactants (APR) such as erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) or other indicators of systemic inflammation (i.e. normocytic anaemia, thrombocytosis, elevated fibrinogen levels, or abnormalities in serum protein electrophoresis (SPEP) like reduced albumin and heightened alpha2 and alpha1 fractions) [5]. The gene discussed is CRP; the disease is thrombocytosis disease.