Rtel1 gene amplification has been observed in gastrointestinal cancer and adrenocortical carcinoma (Bai et al., 2000; Yuan et al., 2022) and Rtel1 single‐nucleotide polymorphisms have been associated with increased susceptibility to glioma (Melin et al., 2017; Namgoong et al., 2018; Shete et al., 2009; Wrensch et al., 2009; Wu et al., 2019) underlying a key role for RTEL1 in cancer development (Hassani et al., 2023). Here, RTEL1 is linked to adrenal cortex carcinoma.