Besides, a model of triallelic inheritance of BBS genes was suggested for Bardet-Biedl syndrome, digenic inheritance of unlinked ROM1 and RDS loci was described for retinitis pigmentosa, and digenic trans-heterozygous inheritance of KIF14 and TMEM67 genes—for Meckel Gruber syndrome [70–72]. The gene discussed is TMEM67; the disease is Meckel syndrome.