TERT and stroke disorder: found a significant association between the additive model of rs2853668 and ischemic stroke (HRR = 1.17, p = 0.05, 95% CI = 1.00–1.38).Han et al. [17] showed that the T/G and G/G genotypes of rs2736100 and the G/A and A/A genotypes of rs2853676 were associated with stroke risk (P < 0.05).This study was the first to assess the link between TERT SNPs and CSVD risk, ultimately revealing that rs2853676 and rs2075786 were significantly associated with CSVD even following Bonferroni correction.