DYNLT1 co-localizes with Voltage-Dependent Anion Channel 1 (VDAC1) on the mitochondria, regulating essential metabolic and energy functions, thereby promoting proliferation, migration, invasion, and mitochondrial metabolism of breast cancer cells in vitro, and facilitating the development of breast tumors in vivo (Huang et al. 2023). Here, VDAC1 is linked to breast neoplasm.