At the same time, MCL1 is among the most highly overexpressed pathologic proteins across all cancers2, including solid tumor malignancies in liver17, breast18, non-small cell lung (NSCLC)19, urothelial20 or pancreatic cancer21, as well as hematological cancers including acute myeloid or chronic lymphocytic leukemia22,23 and non-Hodgkin lymphoma24. Here, MCL1 is linked to hematopoietic and lymphoid cell neoplasm.