Analysis of EP300 expression in one normal renal cell line (HK2) and two ccRCC cell lines (786-O and Caki-1) through qRT-PCR (Fig. 4H) and WB (Fig. 4I) revealed consistency with the tissue results, indirectly implying the presence of PTM in EP300. This evidence concerns the gene EP300 and nonpapillary renal cell carcinoma.