The slower tumor growth in Tnfr1−/− mice was not cell line specific, as the growth of the Panc02 murine pancreatic cell line was also reduced in Tnfr1−/− mice (Figure S1B), which was accompanied by increased numbers of tumor-infiltrating immune cells and higher percentages of IFN-γ-producing CD4+ and CD8+ T cells (Figures S1C and S1D). Here, CD4 is linked to neoplasm.