FLT3LG and neoplasm: Furthermore, the levels of MHC-II expressed on tumor-infiltrating DCs, a measure of their maturational and functional state, were much lower in anti-CD40+Flt3L-treated mice compared to control, whereas MHC-II levels on DCs from anti-TNFR1-treated mice were similar to if not greater than control mice (Figure 6E).