Measurement of chemokines in the lung showed several alterations in global IFNLR1-/- mice compared to WT mice both during super-infection and single S. aureus infection, including increased TNFα, CXCL11, CXCL12, and MIP3α and decreased IL-1β, MIP1β, and CXCL16 (Fig 1F). This evidence concerns the gene TNF and infection.