Among the mRNAs showing interactions with biomarker candidate miRNAs in this study (hsa-miR-181b, hsa-miR-143, hsa-miR-130a, hsa-miR-224, hsa-miR-188, and hsa-miR-501, Table 2), DDIT4, PLA2G4A, RAB27B, CD163, CALCRL, SLC8A1, CRISPLD1, SCHIP1, LGALSL, SORT1, PDE7B, HTR1F, CLIP4, PRDM16, RTN1, KCNJ2, CPNE8, KIAA0087, FHL1, STOX2, GLIS3, and ADAMTS3 were significantly correlated with the survival of patients with AML in the TCGA database analysis (Fig 5). Here, CPNE8 is linked to acute myeloid leukemia.