Elevated AST, elevated ALT, vomiting, reduced neutrophil count, reduced leukocyte count, sinus bradycardia, diarrhea, elevated CPK, nausea, neurotoxicity (dysgeusia or dizziness), constipation, elevated LDH, elevated CK-MB, ocular disorders, elevated creatine, hypoproteinemia, anemia, and peripheral edema. The gene discussed is GPT; the disease is Peripheral edema.