Vascular EDS, an autosomal dominant genetic disorder caused by mutations in the type III collagen gene (COL3A1), is estimated to occur in approximately 5% of all patients with EDS (approximately 1 in 50,000–200,000), with 77% reported to have serious complications such as arterial rupture, dissection, or aneurysm [4, 5]. Here, COL3A1 is linked to Ehlers-Danlos syndrome, vascular type.