In multivariable Cox regression analyses incorporating sex, age, UICC stage, tumour location (right‐ versus left‐sided), conventional histopathological parameters (tumour budding, WHO grade, and histopathological subtype), presence/absence of lymphatic/blood vessel invasion, resection status as well as p53 and MSI status, TROP2 expression was not an independent prognostic factor (OS: HR: 1.09, p = 0.45, data not shown; DSS: HR: 1.04, p = 0.73, data not shown; and DFS: HR: 1.19, p = 0.167, Table 2). Here, TP53 is linked to neoplasm.