To compare the effects of priming on the capacity of cADSCs to inhibit Th-cell proliferation, cADSCs were primed with colon homogenate as well as purified inflammatory cytokines (TNF-α+IFN-γ), serum or liver homogenate from colitis mice for 24 h, after which co-culture assays were performed with primed cells and Th cells derived from mice with colitis. The gene discussed is TNF; the disease is colitis.