Both naive cADSCs and cADSCs primed with any condition reduced F4/80+ CD80+ M1 macrophages, which were drastically increased by colitis induction, but cADSCs primed with TNF-α+IFN-γ or colon homogenate in particular significantly and markedly reduced them (Supplementary Figures 3A, B). Here, TNF is linked to colitis.