T-cell surface glycoprotein CD6 isoform levels (CD6) (OR = 0.858, 95% CI = 0.737 ~ 0.999, P = 0.049) and Cystatin D levels (OR = 0.808, 95% CI = 0.695 ~ 0.940, P = 0.006) were associated with a decreased risk of sepsis (28-day mortality) (Supplementary Table S4). This evidence concerns the gene CST5 and Sepsis.