LRBA and cancer: Next, we acquired the top 10 PPA2-correlated genes from all TCGA tumors and normal tissues, among these genes, LAMTOR3, CDS1, EIF4E, LRBA, PLA2G12A, and ARFIP1) showed high correlations (all r>0.05,p<0.05)with PPA2 (Figure 5B); in addition, the Timer database showed that these genes (CDSA, EIF4E, LRBA PLA2G12A, and ARFIP1) are closely related to PPA2 in the majority of cancer types (Figure 5C).