EXOSC3 and non-small cell lung carcinoma: To assess the combined effect of these two independent SNPs on NSCLC survival, we combined unfavorable genotypes (INPP5D rs13385922 CT+TT and EXOSC3 rs3208406 AG+GG) into a genetic score and divided all NSCLC patients into three groups (i.e., 0, 1, and 2) according to the number of unfavorable genotypes (NUGs).