The AuNP‐Pc158 conjugates were completely quenched, but upon interaction with the cathepsin overexpressed in prostate tumor, the GLFGC linker was cleaved and released the free Pc158, thereby eliminating the quenching effect and switching on the fluorescent signal for prostate tumor detecting with a high specificity and sensitivity.[36] Fan et al. This evidence concerns the gene CTSS and prostate neoplasm.