GZMB and colon adenocarcinoma: For instance, Nguyen and co‐workers used a granzyme B‐responsive IEPD linker to design a granzyme B‐responsive nanoreporter (GNR) by conjugating a dye‐quencher (5‐carboxyfluorescein‐QSY‐7) to a polymer backbone (PIMA) for tracking granzyme B activity and further monitoring the immunotherapy efficacy of MC38 colon adenocarcinoma tumor.