Multivariate analysis confirmed that the EP-TF model risk score was a strong independent prognostic factor across all NB cohorts (HR = 1.923, p < 0.001 in GSE62564; HR = 1.545, p = 0.01 in EGAS; HR = 1.831, p = 0.002 in GSE16476) (Figure 8D). This evidence concerns the gene TF and neuroblastoma.