Numerous studies have demonstrated a correlation between elevated VEGFR1 levels and COVID-19 severity, as well as the ICU admission of COVID-19 patients (Krock et al., 2011; Ackermann et al., 2020; Nagashima et al., 2020; Pine et al., 2020; Miggiolaro et al., 2023; Pius-Sadowska et al., 2023). This evidence concerns the gene FLT1 and COVID-19.