Our analysis, however, uncovered that proteins encoded by ten genes (MAPT, HLA-B, HLA-C, HLA-F, HLA-DQA2, HLA-DOB, TAP2, PSMB9, TYK2, MICB) regulated by spatial eQTLs associated with psoriatic arthritis, directly interact with proteins encoded by nine JIA causal genes. The gene discussed is TYK2; the disease is juvenile idiopathic arthritis.