CPT2 and melanoma: P3-S melanoma cells express higher levels with respect to S melanoma cells of carnitine palmitoyl-transferases CPT1 and CPT2, which are mitochondrial enzymes responsible for the formation of acylcarnitines by catalyzing the transfer of the acyl group of a long-chain fatty acyl-CoA from coenzyme A to l-carnitine (Figure 4B).