Moreover, since a stem-like phenotype sustains cancer cell survival after detachment from ECM, we evaluated the expression of SOX2, OCT3/4, KFL4 and ALDH1 stemness markers and we found that p3 anoikis-resistant cells show a tendency to increase the expression of these markers, especially ALDH1 (Figure 2D). The gene discussed is ALDH1A1; the disease is cancer.