ADA and Miyoshi myopathy: Among these DEGs, Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses revealed that upregulated DEGs were mainly enriched in multiple cell death pathways, such as ferroptosis, mitophagy, apoptosis, phagosome, and autophagy pathways (Figure 3B), aligning with previous observations that ADA significantly propels MM cell death.