KCNQ2 and infantile spasms: Recently, GoF variants in the KCNQ2 gene were described, causing a distinct phenotype with profound developmental delay, neonatal non-epileptic myoclonus, and later onset epilepsy such as infantile spasms (Miceli et al., 2015; Millichap et al., 2017; Mulkey et al., 2017; Miceli et al., 2022).