ELN and cancer: PAS canmeticulously highlight the spatial distribution of keymolecules like collagen, elastin, lipids, melanin, water, and manyothers within breast tissues, empowering clinicians to gain an unparalleledunderstanding of the structural alterations in elastin deposition,collagen density, angiogenesis, and other biomolecule metabolism accompanyingtumorigenesis.146 For instance, recentstudies have suggested that the amount and structural alteration ofcollagen in the ECM are strongly linked to the growth and metastasisof cancer cells.