Moreover, correlation analysis between the CLDN7 expression and pathological features in 908 BC samples (TCGA) with complete clinical information revealed that the altered expression of CLDN7 could be associated with expressions of the estrogen receptor coding gene ESR1 and the human epidermal growth factor receptor encoding gene ERBB2 (All P < 0.05; Table 1). The gene discussed is ERBB2; the disease is breast cancer.