In summary, we found that similar to vascular cells from patients with PAH (Dromparis et al., 2010; Lampron et al., 2020; Meloche et al., 2015), PASMCs from the SuHx rat model of PH are resistant to apoptosis via a mechanism involving AQP1‐mediated increases in Bcl‐2 expression. This evidence concerns the gene AQP1 and pulmonary arterial hypertension.