In many types of cancer cells, AQP1 protein levels are elevated and inversely correlated with susceptibility to apoptosis (Lehnerdt et al., 2015; Moosavi & Elham, 2020; Simone et al., 2018; Tomita et al., 2017), although in other tumor cells (i.e., mesothelioma) AQP1 and apoptosis were not associated (Klebe et al., 2015). Here, AQP1 is linked to neoplasm.