STAT3 and lung adenocarcinoma: Summarizing our discussion of ROP16 function, amino acid polymorphisms and STAT3 phosphorylation sites, in our next work we will first explore the effects of amino acid sequence differences among the three genotypes of ROP16 on lung adenocarcinoma cell phenotypes and STAT3 phosphorylation as a means of identifying the major amino acid sites responsible for the difference in function between type I/III ROP16 and type II ROP16 in lung adenocarcinoma cells.