SMARCA4 and cancer: SMARCA4 and SMARCA2 have emerged as oncogenic dependencies in certain cancer types, with SMARCA4 specifically being implicated in cancer metastasis (Farnaby et al, 2019; Huang et al, 2018; Kofink et al, 2022; Papillon et al, 2018; Saladi et al, 2010; Xiao et al, 2022).