TP53 and neoplasm: In total, readthrough >2% can be achieved by at least one drug for 43/102 PTCs in TP53. Considering all 102 PTCs, SJ6986 is the most effective drug for 36 PTCs, DAP for 25 PTCs, clitocine for 21 PTCs, SRI for 14 PTCs and G418 for 6 PTCs in TP53. Encouragingly, clitocine treatment was shown to impede tumor growth in mice bearing the Q136X_UAA mutation27, which displays a 2.1% readthrough in our dataset.