This study demonstrated changes in the expression of miRNAs (has-miR-19a, hsa-miR-19b, has-miR-375, hsa-miR-29c, miR-29, miR-143/145, miR-17-92, miR-106b-25, and miR-503/424, miR-9, miR-30a, miR-196a2, miR-139-5p, hsa-let-7a, hsa-let-7b, and hsa-miR-486) and lncRNAs (STX18-AS1, HOTAIR, AA709223, BX478947, and Moshe) related to ASD development. Here, STX18 is linked to atrial septal defect.