A cascade of cytokines, marked by the overproduction of inflammatory signaling molecules such as Interleukin (IL)-1, IL-2, IL-6, IL-13, IL-17, Interferon-γ, and TNF-α is identified as a physiological and pathological factor intricately linked to the severity of the Coronavirus disease 2019 (COVID-19) [1, 2]. This evidence concerns the gene TNF and COVID-19.