C1qR1 (CD93) (Supplemental Figure 4E), C3AR1 (Figure 4B), and C5AR1 (Supplemental Figure 4F), but not CR1 (Supplemental Figure 4G) or CR2 (Supplemental Figure 4H), were highly upregulated in GBM compared with normal brain tissue. This evidence concerns the gene C5AR1 and glioblastoma.