As noted above, forced YAP expression did not increase already high UNC5B levels in SCLC lines such as NCI-H2171 and NCI-H209, but YAP-induced Netrin-1 in both contexts (Fig. 3H), and the Netrin-1 antibody and trapping agents alleviated YAP-induced cytostasis in NCI-H2171 and NCI-H209 SCLC cells (Fig. 4C and D). Here, UNC5B is linked to small cell lung carcinoma.