Alternatively, in solid neural and neuroendocrine YAPoff cancers, such as retinoblastoma, small cell lung cancer (SCLC), small cell neuroendocrine prostate cancer, and Merkel cell carcinoma, among others, ectopic YAP/TAZ cooperate with TEAD family proteins to induce cytostasis (1, 3). Here, WWTR1 is linked to cancer.