Mihaela Cristina Buhaş (Buhaş et al., 2023) and colleagues observed the effectiveness of probiotics combined with prebiotics in the treatment of psoriasis patients, and found that after 12 weeks of intervention, inflammatory markers TNF-α, IL-6, IFN-γ in psoriasis patients significantly decreased, and the main inhibitory factor of the immune response IL-10 increased. The gene discussed is IFNG; the disease is psoriasis.