In addition to these results, we also discovered several previously unreported immune cell phenotypes related to AD, including harmful factors such as CD11c+ CD62L-monocyte % monocyte, Im MDSC AC, and CD33 on CD66b++ myeloid cells, as well as protective factors such as CM CD8+ T cell % CD8+ T cell, HLA DR+ T-cell AC, CD25 on switched memory B cell, IgD on transitional B cell, CD16-CD56 on NKT, and SSC-A on HLA DR+ T cell. This evidence concerns the gene CD33 and Alzheimer disease.