The results showed that the following factors were significantly associated with BC: subtype (HR=6.461; 95% CI=2.860~14.595; p<0.001), TNM stage (HR=9.603; 95% CI=4.080~22.602; p<0.001), PLT (HR=1.374; 95% CI=1.016~1.860; p =0.039), LYM (HR=1.748; 95% CI=1.043~2.930; p =0.034), HGB (HR= 0.690; 95% CI=0.510~0.935 p =0.017), AGR (HR=1.951; 95% CI=1.389~2.740; p <0.001), and PA (HR= 0.694;95% CI=0.507~0.949; p =0.022). This evidence concerns the gene CYGB and breast cancer.