Specifically, the transcription factor CEBPA, a promoter of myeloid cell differentiation (20), STAT1, an inhibitor of stemness properties and cell proliferation (21), and NFIC, The TF of has been reported to inhibit pancreatic cancer (22), were found to be substantially upregulated in the CXCL10+ M1 and FOLR2+ M1 macrophages, which demonstrated increased cell counts within the pCR group. Here, FOLR2 is linked to familial pancreatic carcinoma.