CCNE1 and cancer: Relevant literature showed that MECOM and MYC were oncogenes; the high occurrence rate of TERC mutation and the increase of CNV of TERC gene were related to the malignancy of tumors [41]; CASC11 acted as an oncogene in several cancer types [42]; the amplification of CCNE1 gene was more frequent in G3 than G2 in grade grading of endometrial carcinoma [43].