In addition, when right heart dysfunction occurs in SCM patients, the plasma concentration of NT-proBNP is significantly increased, which may be due to the influence of pulmonary infection, acute respiratory distress syndrome, mechanical ventilation and other factors in the occurrence of sepsis, resulting in increased pulmonary vascular resistance, and fluid overload in SCM patients further aggravates the right ventricular load. This evidence concerns the gene NPPB and acute respiratory distress syndrome.