Univariate analysis revealed no significant association between pCR post-nCRT and factors such as gender, ethnicity, BMI, smoking status, alcohol consumption, hypertension, diabetes, pre-nCRT anemia, albumin level, inflammatory markers (NLR, LMR, PLR), CA19-9 levels, and T/N staging pre- and post-nCRT. The gene discussed is ALB; the disease is hypertensive disorder.