TGFBI and corneal dystrophy: For instance, an established corneal dystrophy variant in TGFBI, NM_000358.3: c.1664G > A; p.(Arg555Gln), has predictions of benign or uncertain classification in several in-silico predictors, SIFT = 0.267, EVE = 0.1704, and REVEL = 0.567 (dbNSFP version 4.8).