PHKG2 and neoplasm: RT-qPCR results showed that PHKG2 expression was significantly higher in the post-radiotherapy tumor tissues from radiotherapy-sensitive NSCLC patients than in the pre-radiotherapy tumor tissues from radiotherapy-resistant NSCLC patients; the PHKG2 expression in the tissues of 8/10 patients was elevated after radiotherapy, while there was no significant change in PHKG2 levels between the pre-radiotherapy and post-radiotherapy tumor tissues from radiotherapy-resistant NSCLC patients (Fig. 1H, Supplementary Fig. 3D, E).