CD8A and neoplasm: In contrast to the CD8+ T-cell abundance in the R subgroup, monocytes expressing CD68 were enriched in the NR-subgroup (Mann–Whitney p = 0.04, Fig. 3F) and were correlated with tumour growth (r = 0.51 p = 0.03), but inversely associated with CD45RO+CD8+ T-cells (Spearman’s r = −0.61, p = 0.007 Supplementary Fig. 9A).