BRD2 and central congenital hypothyroidism: As shown in Table 7, ACTH deficiency is reported in 43% to 57% of cases, TSH deficiency in 31% to 57%, FSH/LH deficiency in 8% to 57%, GH deficiency in 37% to 54% and AVP-D in 51% to 70% of cases [129, 131, 134, 136].