TF and glioblastoma: In fact, in xenograft models it was shown that tumors expressing both TF and podoplanin demonstrated increased intravascular fibrin staining and vessel-occluding thrombi when compared to tumors expressing TF or podoplanin only.68Furthermore, tumoral expression of procoagulant proteins in glioblastoma may be highly heterogeneous, representing a mosaic of different glioblastoma subtypes which requires further investigation, e.g., by single-cell RNA sequencing.